Institute of Pharmacy and Molecular Biotechnology Department Pharmaceutical Technology and Biopharmacy
Making the impassable passable for medicine
Prof. Dr. Gert Fricker and his team are focusing on finding innovative ways to transport drugs to where they are urgently needed. They are faced with the exciting challenge of overcoming barriers such as the blood-brain barrier and effectively transporting drugs into the brain. The aim is to make the impassable passable for drugs so that they can develop their full therapeutic effect.
Research Topics
The research of the working group is centered on drug delivery in vivo. To this end, modern in vitro models are being researched and established with the help of which the mechanisms behind the distribution of drugs can be investigated and optimized.
An important hurdle that the group faces is the blood-brain barrier. Possible mechanisms are being sought that can be used to bypass this barrier. This could enable many CNS-active drugs to work more effectively. With the help of target-seeking vectors (e.g. antibodies), active substances can be specifically directed across the blood-brain barrier to their target.
In addition, the group is also researching how to improve drug absorption from the gastrointestinal tract. Improved absorption would enable the oral administration of poorly soluble or peptide drugs.
Information for Applicants
For information on vacancies and possible Bachelor's and Master's theses, please visit the Group's external website. There you will find the right contact person for your inquiries.